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Antioxidants found to be effective in treating mitochondrial disease, preclinical trials find

In search of mitochondrial disease treatments, researchers found that some antioxidant compounds could be effective in treating mitochondrial disease.  In their study, the researchers examined seven antioxidant compounds in two animal models of mitochondrial disease: Zebrafish and the worm species Caenorhabditis elegans. In addition, they used cultures of fibroblasts or skin cells obtained from human patients as a third model. All of the models, the patient cells and the experimental animals, had genetically based malfunctions of the mitochondrial respiratory chain. This is an essential part of the mitochondria wherein cells process nutrients and oxygen to produce chemical energy.  Read more...



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