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Commonly prescribed drugs are tied to nearly 50% higher dementia risk in older adults, study says

Scientists have long found a possible link between anticholinergic drugs and an increased risk of dementia.  A study published in the journal JAMA Internal Medicine on Monday suggests that the link is strongest for certain classes of anticholinergic drugs -- particularly antidepressants, bladder antimuscarinics, antipsychotics and antiepileptic drugs.  Researchers wrote in the study that "there was nearly a 50% increased odds of dementia" associated with a total anticholinergic exposure of more than 1,095 daily doses within a 10-year period, which is equivalent to an older adult taking a strong anticholinergic medication daily for at least three years, compared with no exposure.  Read more...

 

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