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Evolving alongside other bacteria keeps hospital bug potent

Bacteria that evolve in natural environments -- rather than laboratory tests -- may become resistant to phage treatments without losing their virulence, new research shows.  The University of Exeter study examined why Pseudomonas aeruginosa bacteria develop resistance to phages (viruses that kill bacteria) in different ways in labs and the real world. In labs, bacterial evolution tends to result in the loss of a receptor to which phages usually attach. In natural environments, the bacteria tend to evolve resistance based on an immune mechanism called CRISPR-Cas.  Read more.....

 

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