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How salt can trigger inflammation in multiple sclerosis

In a new study published Oct. 29 in the journal Nature Immunology, they report just how salt can trigger the potentially disabling autoimmune disorder.  Author Tomokazu Sumida, a researcher in the lab of David Hafler, the William S. and Lois Stiles Edgerly Professor of Neurology and professor of immunobiology, and colleagues report that cells in a high-salt environment show activation of the beta-catenin/Wnt signaling pathway. This pathway, which also been implicated in the development of cancer tumors, disrupts regulatory T cells and triggers inflammation.  Read more...
 

 

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