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New kind of compound shows early promise against prostate cancer

A new type of molecule blocks the action of genes that drive the growth of therapy-resistant prostate cancer, a new study finds.  "Rather than continue making compounds that are just like older drugs, the focus of our work has been to rethink the definition of what a drug-like molecule can be," says corresponding author Susan Logan, Ph.D., associate professor in the Department of Urology, at NYU School of Medicine.  A joint research team from the School of Medicine and New York University found that their "cyclic peptoids" reduced the growth of prostate cancer cells in cultures by 95 percent compared to untreated cells. The experimental drugs also blocked a key, related growth signal in live animal tests.  Read more...

 

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