Girl Planting seeds

Prostate cancer researchers find molecular switch to prolong survival

Wilmot Cancer Institute scientists believe they have figured out why a commonly used drug to treat late-stage prostate cancer often stops working after four or five months and appears to have a dual function that later turns the cancer into a relentless aggressor.  By describing how the drug, enzalutamide, inadvertently causes the harmful transformation, corresponding author Chawnshang Chang, Ph.D., and colleagues believe they have also discovered a way to block it from occurring, at least in mice. The study, led by Jie Luo, a graduate student from the Department of Biology at the University of Rochester, was published in the journal Nature Communications.  Read more...



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