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Researchers find vitamin D receptor is target for disruption by environmental chemicals

New research from North Carolina State University sheds light on the ways in which environmental chemicals can affect vitamin D receptors (VDR). The work shows that compounds identified as possible VDR disruptors in the Tox21 database interact with VDR in vitro and supports the efficacy of high throughput screening programs to identify compounds of interest.  Researchers are interested in exploring the effects of environmental chemicals on vitamin D receptors. A team of researchers from NC State and the U.S. Environmental Protection Agency (EPA) looked at compounds that the Tox21 database had flagged as potential VDR disruptors.  Read more...


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