Girl Planting seeds

Researchers putting the brakes on lethal childhood cancer

Malignant rhabdoid tumor (MRT) is one of the most aggressive and lethal childhood cancers.  Although rare -- about 20 to 25 new cases are diagnosed annually in the United States -- there is no standard effective treatment for the disease, which is driven by loss of an anti-cancer protein called SNF5. The chances are very small that a child will survive a year after MRT diagnosis.  Now researchers at Vanderbilt University have discovered that a pro-cancer protein, MYC, is normally inhibited by SNF5. Loss of SNF5 effectively "takes the brakes off" MYC, thus accelerating cancerous growth.  Read more....

 

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