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Widely Used Fungicide Found to Adversely Affect Enzyme Common to All Cells

This is a story about a chemical pesticide, a fungicide, in wide use for which the mode of action, i.e., the ability to cause harm, has not been fully understood. It is not a story unique to this pesticide. Rather, it is an important story to consider when deciding to use a pesticide or allowing a pesticide to be used. The question is whether the chemical could be broadly problematic beyond the target organisms, in this case fungi? In its coverage of a study published in March, the American Association for the Advancement of Science publication, EurekAlert, reported that, “The ability of [the fungicide] fludioxonil to act on a sugar-metabolizing enzyme common to all cells, and to produce the damaging compound methylglyoxal, may mean that the pesticide has more potential to harm non-fungal cells than previously thought. Although fludioxonil has been deemed safe for use, the authors . . . suggest that the effects of this widely used pesticide has upon animals be re-examined.”  Read more...

 

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